Allgemein

Oktober 2022. Das Auftreten des SARS-CoV 2 Virus zeigt auf sehr eindrückliche Weise, wie unsere heutige Gesellschaft immer noch anfällig für hochinfektiöse Atemwegserkrankungen ist. Im Gegensatz zu früheren Pandemien ist es jedoch der modernen Medizin innerhalb weniger Wochen nach dem weltweiten Auf...

Dr. Sonja Kirsch wurde von der Naturwissenschaftlichen Fakultät der FAU mit dem Karl Giehrl Promotionspreis ausgezeichnet. In ihrer Dissertation (AG Böckmann) hat Frau Kirsch die Aufklärung der Aktivierung von sogenannten Zweiporenkanälen vorangetrieben und herausragende Beiträge zum Verständnis von...

September 2019. Dendritic cells (DCs) are key players in the immune system as they orchestrate the initiation of immune responses, but also the induction of tolerance. DC signaling response and the host recognition of invading pathogens primarily rely on receptors that are highly expressed on the ce...

June 2019. Our study characterizes the structure and dynamics of phospholipid bilayers close to phase transition employing atomistic molecular dynamics simulations. The simulations recover not only the well-studied first-order transition with discontinuities in the area per lipid or membrane thickne...

December 2017. Liping Sun of the Computational Biology group successfully defended her thesis with the title „Biomembrane Dynamics: From Membrane Thermodynamics to Protein Design“. Congratulations!

November 2016. SNARE peptides act cooperatively during synaptic vesicle fusion. It has previously been suggested that oligomerization of SNARE complexes, which is required for cooperative action in fusion is mediated by interactions between their transmembrane domains (TMDs) and further tuned by int...

November 2016. Combination of NMR and CD experiments with MD simulations revealed the dual role of the model fusion peptide K in aiding membrane fusion. Next to the before known function of peptide K to form a coiled-coil complex with peptide E and thus to link the fusion vesicles, the membrane-dist...

November 2016. Simulations reveal new insights into the function of a protein involved in cancer metastasis and AIDS Cholesterol may act as a selective glue that binds proteins into paired structures that enable human cells to respond to outside signals, according to our new study in PLOS Computa...

August 2016. Zhenyan Jiang of the Computational Biology group successfully defended his thesis with the title "BAX Activation and Oligomerization in Membranes Studied by Coarse-Grained and All-Atom Simulations". Congratulations!